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Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data

BACKGROUND: Understanding cellular and molecular heterogeneity in glioblastoma (GBM), the most common and aggressive primary brain malignancy, is a crucial step towards the development of effective therapies. Besides the inter-patient variability, the presence of multiple cell populations within tum...

詳細記述

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書誌詳細
出版年:BMC Bioinformatics
主要な著者: Lopes, Marta B., Vinga, Susana
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029554/
https://ncbi.nlm.nih.gov/pubmed/32070274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3390-4
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