Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway

Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of only 1–4%. Integrin-mediated cell adhesion is critical for the initiation, progression, and metastasis of cancer. In this study we investigated the role of integrin β4 (ITGB4) and its phosphorylation at tyr...

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Publicado en:Bosn J Basic Med Sci
Autores principales: Meng, Xiangli, Liu, Peng, Wu, Yunhao, Liu, Xinlu, Huang, Yinpeng, Yu, Boqiang, Han, Jiahong, Jin, Haoyi, Tan, Xiaodong
Formato: Artigo
Lenguaje:Inglês
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029197/
https://ncbi.nlm.nih.gov/pubmed/31242404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2019.4255
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