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Cross-linking modifications of HDL apoproteins by oxidized phospholipids: structural characterization, in vivo detection, and functional implications

Apolipoprotein A-I (apoA-I) is cross-linked and dysfunctional in human atheroma. Although multiple mechanisms of apoA-I cross-linking have been demonstrated in vitro, the in vivo mechanisms of cross-linking are not well-established. We have recently demonstrated the highly selective and efficient mo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gao, Detao, Ashraf, Mohammad Z., Zhang, Lifang, Kar, Niladri, Byzova, Tatiana V., Podrez, Eugene A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029106/
https://ncbi.nlm.nih.gov/pubmed/31907281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008445
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