Cross-linking modifications of HDL apoproteins by oxidized phospholipids: structural characterization, in vivo detection, and functional implications

Apolipoprotein A-I (apoA-I) is cross-linked and dysfunctional in human atheroma. Although multiple mechanisms of apoA-I cross-linking have been demonstrated in vitro, the in vivo mechanisms of cross-linking are not well-established. We have recently demonstrated the highly selective and efficient mo...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Gao, Detao, Ashraf, Mohammad Z., Zhang, Lifang, Kar, Niladri, Byzova, Tatiana V., Podrez, Eugene A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029106/
https://ncbi.nlm.nih.gov/pubmed/31907281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008445
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