Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function

BACKGROUND: Genome-wide association studies (GWASes) have identified many noncoding germline single-nucleotide polymorphisms (SNPs) that are associated with an increased risk of developing cancer. However, how these SNPs affect cancer risk is still largely unknown. METHODS: We used a systems biology...

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Udgivet i:Br J Cancer
Main Authors: Fagny, Maud, Platig, John, Kuijjer, Marieke Lydia, Lin, Xihong, Quackenbush, John
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028992/
https://ncbi.nlm.nih.gov/pubmed/31806877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0614-3
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