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PARP inhibitor Olaparib increases the sensitization to radiotherapy in FaDu cells

Radioresistance causes a major problem for improvement of outcomes of patients treated with radiation. Targeting for DNA repair deficient mechanisms is a hallmark of sensitization to resistance. We tested whether Olaparib, a (poly) ADP‐ribose polymerase (PARP) inhibitor, can sensitize the radioresis...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Liu, Chuan, Gross, Neil, Li, Yanshi, Li, Guojun, Wang, Zhihai, Zhong, Shixun, Li, Yuncheng, Hu, Guohua
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028864/
https://ncbi.nlm.nih.gov/pubmed/31957270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14929
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