High‐fat diet‐induced dysbiosis mediates MCP‐1/CCR2 axis‐dependent M2 macrophage polarization and promotes intestinal adenoma‐adenocarcinoma sequence

High‐fat diet (HFD) is a well‐known risk factor for gut microbiota dysbiosis and colorectal cancer (CRC). However, evidence relating HFD, gut microbiota and carcinogenesis is limited. Our study aimed to demonstrate that HFD‐induced gut dysbiosis promoted intestinal adenoma‐adenocarcinoma sequence. I...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Liu, Tianyu, Guo, Zixuan, Song, Xueli, Liu, Li, Dong, Wenxiao, Wang, Sinan, Xu, Mengque, Yang, Cheng, Wang, Bangmao, Cao, Hailong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028862/
https://ncbi.nlm.nih.gov/pubmed/31957197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14984
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