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Single-Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics
Cell-to-cell heterogeneity can substantially impact drug response, especially for monoclonal antibody (mAb) therapies that may exhibit variability in both delivery (pharmacokinetics) and action (pharmacodynamics) within solid tumors. However, it has traditionally been difficult to examine the kineti...
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| Publicado no: | Cytometry A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7028488/ https://ncbi.nlm.nih.gov/pubmed/31423731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23872 |
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