Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity

Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the “cancer-immunity cycle” in the pan-cancer setting in order to understand the immune landscape of metastati...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Kato, Shumei, Okamura, Ryosuke, Kumaki, Yuichi, Ikeda, Sadakatsu, Nikanjam, Mina, Eskander, Ramez, Goodman, Aaron, Lee, Suzanna, Glenn, Sean T., Dressman, Devin, Papanicolau-Sengos, Antonios, Lenzo, Felicia L., Morrison, Carl, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028323/
https://ncbi.nlm.nih.gov/pubmed/32117584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1708065
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