Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis

Interleukin-32 is a novel inflammatory mediator that has been described to be important in the immunopathogenesis and control of infections caused by Leishmania parasites. By performing experiments with primary human cells in vitro, we demonstrate that the expression of IL-32 isoforms is dependent o...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: dos Santos, Jéssica Cristina, Leite Quixabeira, Valéria Bernadete, Teodoro Silva, Muriel Vilela, Damen, Michelle S. M. A., Schraa, Kiki, Jaeger, Martin, Oosting, Marije, Keating, Samuel T., Dorta, Miriam Leandro, Alves Pinto, Sebastião, Bugalho Duarte, Fernanda, de Araújo Pereira, Ledice Inácia, Netea, Mihai G., Ribeiro-Dias, Fátima, Joosten, Leo A. B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028298/
https://ncbi.nlm.nih.gov/pubmed/32023240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008029
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