Susceptibility of monomicrobial or polymicrobial biofilms derived from infected diabetic foot ulcers to topical or systemic antibiotics in vitro

Diabetic foot ulcers can become chronic and non-healing despite systemic antibiotic treatment. The penetration of systematically-administered antibiotics to the site of infection is uncertain, as is the effectiveness of such levels against polymicrobial biofilms. We have developed an in vitro model...

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Bibliographic Details
Published in:PLoS One
Main Authors: Price, Bianca L., Morley, Robert, Bowling, Frank L., Lovering, Andrew M., Dobson, Curtis B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028275/
https://ncbi.nlm.nih.gov/pubmed/32069293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228704
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