Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases

DO (HLA-DO, in human; murine H2-O) is a highly conserved nonclassical major histocompatibility complex class II (MHC II) accessory molecule mainly expressed in the thymic medulla and B cells. Previous reports have suggested possible links between DO and autoimmunity, Hepatitis C (HCV) infection, and...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Welsh, Robin A., Song, Nianbin, Foss, Catherine A., Boronina, Tatiana, Cole, Robert N., Sadegh-Nasseri, Scheherazade
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028248/
https://ncbi.nlm.nih.gov/pubmed/32069316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000590
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