Anti-Leishmanial and Immunomodulatory Effects of Epigallocatechin 3-O-Gallate on Leishmania tropica: Apoptosis and Gene Expression Profiling

BACKGROUND: Pentavalent antimonials such as meglumine antimoniate (MA, Glucantime), are the first-line treatment against leishmaniasis, but at present, they have basically lost their efficacy. This study was aimed to explore epigallocatechin 3-O-gallate (EGCG), alone or in combination with MA agains...

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Vydáno v:Iran J Parasitol
Hlavní autoři: SADUQI, Morteza, SHARIFI, Iraj, BABAEI, Zahra, KEYHANI, Alireza, MOSTAFAVI, Mahshid, HAKIMI PARIZI, Maryam, GHASEMIAN, Mahdiyeh, BAMOROVAT, Mehdi, SHARIFI, Fatemeh, AFLATOONIAN, Mohammad Reza, SHARIFIFAR, Fariba, GHASEMI NEJAD, Pooya, KHOSRAVI, Ahmad, SALARKIA, Ehsan, VARMA, Rajender S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Tehran University of Medical Sciences 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028242/
https://ncbi.nlm.nih.gov/pubmed/32099555
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