CD4(+)CCR6(+) T cells, but not γδ T cells, are important for the IL‐23R‐dependent progression of antigen‐induced inflammatory arthritis in mice

IL‐23 plays an important role in the development of arthritis and the IL‐23 receptor (IL‐23R) is expressed on different types of T cells. However, it is not fully clear which IL‐23R(+) T cells are critical in driving T cell‐mediated synovitis. We demonstrate, using knock‐in IL‐23R‐GFP reporter (IL‐2...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Razawy, Wida, Asmawidjaja, Patrick S., Mus, Anne‐Marie, Salioska, Nazike, Davelaar, Nadine, Kops, Nicole, Oukka, Mohamed, Alves, C. Henrique, Lubberts, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Immunodeficiencies and autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028107/
https://ncbi.nlm.nih.gov/pubmed/31778214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948112
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