The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma

E3 ubiquitin ligases primarily determine the substrate specificity of the ubiquitin‐proteasome system and play an essential role in the resistance to bortezomib in multiple myeloma (MM). Neural precursor cell‐expressed developmentally downregulated gene 4‐1 (NEDD4‐1, also known as NEDD4) is a foundi...

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Bibliografske podrobnosti
izdano v:Int J Cancer
Main Authors: Huang, Xi, Gu, Huiyao, Zhang, Enfan, Chen, Qingxiao, Cao, Wen, Yan, Haimeng, Chen, Jing, Yang, Li, Lv, Ning, He, Jingsong, Yi, Qing, Cai, Zhen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Molecular Cancer Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027789/
https://ncbi.nlm.nih.gov/pubmed/31390487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32615
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