The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma

E3 ubiquitin ligases primarily determine the substrate specificity of the ubiquitin‐proteasome system and play an essential role in the resistance to bortezomib in multiple myeloma (MM). Neural precursor cell‐expressed developmentally downregulated gene 4‐1 (NEDD4‐1, also known as NEDD4) is a foundi...

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Vydáno v:Int J Cancer
Hlavní autoři: Huang, Xi, Gu, Huiyao, Zhang, Enfan, Chen, Qingxiao, Cao, Wen, Yan, Haimeng, Chen, Jing, Yang, Li, Lv, Ning, He, Jingsong, Yi, Qing, Cai, Zhen
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Molecular Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027789/
https://ncbi.nlm.nih.gov/pubmed/31390487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32615
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