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Preclinical safety assessment of pathogen reduced red blood cells treated with amustaline and glutathione

BACKGROUND: The nucleic acid targeted pathogen reduction (PR) system utilizing amustaline (S‐303) and glutathione (GSH) is designed to inactivate blood‐borne pathogens and leukocytes in red blood cell concentrates (PR‐RBCC). Inactivation is attained after amustaline intercalates and forms covalent n...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: North, Anne K., Mufti, Nina, Sullivan, Theresa, Corash, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027779/
https://ncbi.nlm.nih.gov/pubmed/31930533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15662
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