A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation

Controlling the functional dynamics of DNA within living cells is essential in biomedical research. Epigenetic modifications such as DNA methylation play a key role in this endeavour. DNA methylation can be controlled by genetic means. Yet there are few chemical tools available for the spatial and t...

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發表在:Angew Chem Int Ed Engl
Main Authors: Nguyen, Ha Phuong, Stewart, Sabrina, Kukwikila, Mikiembo N., Jones, Sioned Fôn, Offenbartl‐Stiegert, Daniel, Mao, Shiqing, Balasubramanian, Shankar, Beck, Stephan, Howorka, Stefan
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027477/
https://ncbi.nlm.nih.gov/pubmed/30773767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201901139
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