Iron oxides nanoparticles (IOs) exposed to magnetic field promote expression of osteogenic markers in osteoblasts through integrin alpha-3 (INTa-3) activation, inhibits osteoclasts activity and exerts anti-inflammatory action

BACKGROUND: Prevalence of osteoporosis is rapidly growing and so searching for novel therapeutics. Yet, there is no drug on the market available to modulate osteoclasts and osteoblasts activity simultaneously. Thus in presented research we decided to fabricate nanocomposite able to: (i) enhance oste...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nanobiotechnology
Prif Awduron: Marycz, K., Sobierajska, P., Roecken, M., Kornicka-Garbowska, K., Kępska, M., Idczak, R., Nedelec, J.-M., Wiglusz, R. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027282/
https://ncbi.nlm.nih.gov/pubmed/32070362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00590-w
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