Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes

BACKGROUND: Diabetes mellitus is characterized by chronic vascular inflammation leading to pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform alternatively-spliced (as) TF. Blood-borne TF promotes factor (F) Xa generation resulting in a pro-thrombotic sta...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Witkowski, Marco, Witkowski, Mario, Saffarzadeh, Mona, Friebel, Julian, Tabaraie, Termeh, Ta Bao, Loc, Chakraborty, Aritra, Dörner, Andrea, Stratmann, Bernd, Tschoepe, Diethelm, Winter, Samantha J., Krueger, Andreas, Ruf, Wolfram, Landmesser, Ulf, Rauch, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027062/
https://ncbi.nlm.nih.gov/pubmed/32066445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-0993-z
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