Granulocyte colony-stimulating factor attenuates myocardial remodeling and ventricular arrhythmia susceptibility via the JAK2-STAT3 pathway in a rabbit model of coronary microembolization

BACKGROUND: Coronary microembolization (CME) has a poor prognosis, with ventricular arrhythmia being the most serious consequence. Understanding the underlying mechanisms could improve its management. We investigated the effects of granulocyte colony-stimulating factor (G-CSF) on connexin-43 (Cx43)...

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Veröffentlicht in:BMC Cardiovasc Disord
Hauptverfasser: Wang, Weiwei, Ye, Shuhua, Zhang, Lutao, Jiang, Qiong, Chen, Jianhua, Chen, Xuehai, Zhang, Feilong, Wu, Hangzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026986/
https://ncbi.nlm.nih.gov/pubmed/32066388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-020-01385-5
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