A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons

The histone demethylase LSD1 is a key chromatin regulator that is often deregulated in cancer. Its ortholog, dLsd1 plays a crucial role in Drosophila oogenesis; however, our knowledge of dLsd1 function is insufficient to explain its role in the ovary. Here, we have performed genome-wide analysis of...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Lepesant, Julie M J, Iampietro, Carole, Galeota, Eugenia, Augé, Benoit, Aguirrenbengoa, Marion, Mercé, Clemèntine, Chaubet, Camille, Rocher, Vincent, Haenlin, Marc, Waltzer, Lucas, Pelizzola, Mattia, Di Stefano, Luisa
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026653/
https://ncbi.nlm.nih.gov/pubmed/31799607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1142
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