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Cell-line specific RNA editing patterns in Trypanosoma brucei suggest a unique mechanism to generate protein variation in a system intolerant to genetic mutations

Trypanosoma brucei possesses a highly complex RNA editing system that uses guide RNAs to direct the insertion and deletion of uridines in mitochondrial mRNAs. These changes extensively alter the target mRNAs and can more than double them in length. Recently, analyses showed that several of the edite...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kirby, Laura E, Koslowsky, Donna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026638/
https://ncbi.nlm.nih.gov/pubmed/31840176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1131
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