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Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
The healing of broken chromosomes by de novo telomere addition, while a normal developmental process in some organisms, has the potential to cause extensive loss of heterozygosity, genetic disease, or cell death. However, it is unclear how de novo telomere addition (dnTA) is regulated at DNA double-...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7026635/ https://ncbi.nlm.nih.gov/pubmed/31828313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1109 |
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