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In vitro replicative fitness of early Transmitted founder HIV-1 variants and sensitivity to Interferon alpha

Type I interferons, particularly interferon-alpha (IFN-α), play a vital role in the host's anti-viral defenses by interfering with viral replication. However, the virus rapidly evolves to exploit the IFN-α response for its replication, spread, and pathogenic function. In this study, we attempte...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ashok kumar, Manickam, Sonawane, Aanand, Sperk, Maike, Tripathy, Srikanth P., Neogi, Ujjwal, Hanna, Luke Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026412/
https://ncbi.nlm.nih.gov/pubmed/32066770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59596-x
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