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Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury

Recent studies reported that DNA methylation was involved in retinal cell death. Methyl-CpG binding domain protein 2 (Mbd2) is one of the DNA methylation readers. Its role and mechanism of regulation remain unclear. The ischemia/reperfusion (I/R) model in mice primary culture retinal ganglion cells...

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Bibliografske podrobnosti
izdano v:Mol Ther Nucleic Acids
Main Authors: Ge, Yanni, Zhang, Ran, Feng, Yuqing, Li, Huiling
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025978/
https://ncbi.nlm.nih.gov/pubmed/32074940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.011
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