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Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis
Tubular epithelia are a basic building block of organs and a common site of cancer occurrence(1–4). During tumourigenesis, transformed cells overproliferate and epithelial architecture is disrupted. The biophysical parameters underlying the adoption of abnormal tumour tissue shapes are, however, not...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7025886/ https://ncbi.nlm.nih.gov/pubmed/30700911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0891-2 |
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