TLR2-Melatonin Feedback Loop Regulates the Activation of NLRP3 Inflammasome in Murine Allergic Airway Inflammation

Toll-like receptor 2 (TLR2) is suggested to initiate the activation of NLRP3 inflammasome, and considered to be involved in asthma. The findings that melatonin modulates TLRs-mediated immune responses, together with the suppressing effect of TLRs on endogenous melatonin synthesis, support the possib...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Hui-Mei, Zhao, Cui-Cui, Xie, Qiu-Meng, Xu, Juan, Fei, Guang-He
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025476/
https://ncbi.nlm.nih.gov/pubmed/32117301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00172
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