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Na(+)/K(+)-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes
Compromised Na(+)/K(+)-ATPase function is associated with the occurrence of spreading depolarization (SD). Mutations in ATP1A2, the gene encoding the α2 isoform of the Na(+)/K(+)-ATPase, were identified in patients with familial hemiplegic migraine type 2 (FHM2), a Mendelian model disease for SD. Th...
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| 發表在: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7025397/ https://ncbi.nlm.nih.gov/pubmed/30819023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19833757 |
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