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Design of a randomized controlled phase III study of dose dense methotrexate, vinblastine, doxorubicin and cisplatin (dd-MVAC) or gemcitabine and cisplatin (GC) as peri-operative chemotherapy for patients with locally advanced transitional cell cancer of the bladder. The French GETUG/AFU V05 VESPER trial

The main objective of the French GETUG/AFU V05 VESPER randomized phase III study was to assess the efficacy of dd-MVAC and GC in term of progression-free survival in patients for whom chemotherapy has been decided, before or after surgery. A total of 500 patients have been randomized in 28 reference...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials Commun
Main Authors: Pfister, Christian, Harter, Valentin, Allory, Yves, Radvanyi, François, Culine, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025084/
https://ncbi.nlm.nih.gov/pubmed/32083220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2020.100536
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