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Antithrombotic effect of SP‐8008, a benzoic acid derivative, through the selective inhibition of shear stress‐induced platelet aggregation

BACKGROUND AND PURPOSE: Bleeding is one of the most critical adverse effects of antithrombotic drugs, and many efforts have been made to discover novel antiplatelet agents without bleeding complications. Shear stress‐induced platelet aggregation (SIPA), where the interaction of von Willebrand factor...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ngo, Thien, Kim, Keunyoung, Bian, Yiying, Nam, Gibeom, Park, Hyun‐Ju, Lee, Kiho, Cho, Geum‐Sil, Ryu, Jei‐Man, Lim, Kyung‐Min, Chung, Jin‐Ho
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024737/
https://ncbi.nlm.nih.gov/pubmed/31648364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14894
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