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Comparison of antigenic mutation during egg and cell passage cultivation of H3N2 influenza virus

PURPOSE: When influenza viruses are cultured in eggs, amino acid mutations of the hemagglutinin may occur through egg adaptation. On the other hand, when influenza viruses are cultured in animal cells, no antigenic mutation occurs unlike in eggs. Therefore, we examined whether the antigenic mutation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Vaccine Res
Hauptverfasser: Park, Yong Wook, Kim, Yun Hee, Jung, Hwan Ui, Jeong, Oh Seok, Hong, Eun Ji, Kim, Hun, Lee, Jae Il
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Vaccine Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024727/
https://ncbi.nlm.nih.gov/pubmed/32095441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7774/cevr.2020.9.1.56
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