Hydrogen sulfide regulates muscle RING finger‐1 protein S‐sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy

BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S) plays important roles as a gasotransmitter in pathologies. Increased expression of the E3 ubiquitin ligase, muscle RING finger‐1 (MuRF1), may be involved in diabetic cardiomyopathy. Here we have investigated whether and how exogenous H(2)S alleviates...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Sun, Xiaojiao, Zhao, Dechao, Lu, Fangping, Peng, Shuo, Yu, Miao, Liu, Ning, Sun, Yu, Du, Haining, Wang, Bingzhu, Chen, Jian, Dong, Shiyun, Lu, Fanghao, Zhang, Weihua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024715/
https://ncbi.nlm.nih.gov/pubmed/30734268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14601
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