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A versatile ES cell-based melanoma mouse modeling platform

The cumbersome and time-consuming process of generating new mouse strains and multi-allelic experimental animals often hinders the use of genetically engineered mouse models (GEMM) in cancer research. Here, we describe the development and validation of an embryonic stem cell (ESC)-GEMM platform for...

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Publicado en:Cancer Res
Autores principales: Bok, Ilah, Vera, Olga, Xu, Xiaonan, Jasani, Neel, Nakamura, Koji, Reff, Jordan, Nenci, Arianna, Gonzalez, Jose G., Karreth, Florian A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024666/
https://ncbi.nlm.nih.gov/pubmed/31744817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2924
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