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Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes

Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells. Monocytes are a stromal cell subset whose metabolism is modulated by the microenvir...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Rundgren, Ida Marie, Ryningen, Anita, Anderson Tvedt, Tor Henrik, Bruserud, Øystein, Ersvær, Elisabeth
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024334/
https://ncbi.nlm.nih.gov/pubmed/31963193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020367
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