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A Novel Dual Fluorochrome Near-Infrared Imaging Probe for Potential Alzheimer’s Enzyme Biomarkers-BACE1 and Cathepsin D

A molecular imaging probe to fluorescently image the β-site of the amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cathepsin D (CatD) enzymes associated with Alzheimer’s disease (AD) was designed and synthesized. This imaging probe was built upon iron oxide nanoparticles (cross-linked...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tam, Jenny M., Josephson, Lee, Pilozzi, Alexander R., Huang, Xudong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024167/
https://ncbi.nlm.nih.gov/pubmed/31936569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020274
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