Petromurin C Induces Protective Autophagy and Apoptosis in FLT3-ITD-Positive AML: Synergy with Gilteritinib

Treatment of acute myeloid leukemia (AML) remains inefficient due to drug resistance and relapse, particularly in patients with FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD). Marine-derived natural products have recently been used for drug development against AML. We show in th...

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Bibliografische gegevens
Gepubliceerd in:Mar Drugs
Hoofdauteurs: Ha, You Na, Song, Sungmi, Orlikova-Boyer, Barbora, Cerella, Claudia, Christov, Christo, Kijjoa, Anake, Diederich, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024157/
https://ncbi.nlm.nih.gov/pubmed/31963113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18010057
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