Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial

BACKGROUND: Patients with human papillomavirus-positive (HPV+) oropharyngeal squamous cell carcinoma (OPC) have substantially better treatment response and overall survival (OS) than patients with HPV-negative disease. Treatment options for HPV+ OPC can involve either a primary radiotherapy (RT) app...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Cancer
Main Authors: Nichols, Anthony C., Lang, Pencilla, Prisman, Eitan, Berthelet, Eric, Tran, Eric, Hamilton, Sarah, Wu, Jonn, Fung, Kevin, de Almeida, John R., Bayley, Andrew, Goldstein, David P., Eskander, Antoine, Husain, Zain, Bahig, Houda, Christopoulous, Apostolos, Hier, Michael, Sultanem, Khalil, Richardson, Keith, Mlynarek, Alex, Krishnan, Suren, Le, Hien, Yoo, John, MacNeil, S. Danielle, Mendez, Adrian, Winquist, Eric, Read, Nancy, Venkatesan, Varagur, Kuruvilla, Sara, Warner, Andrew, Mitchell, Sylvia, Corsten, Martin, Rajaraman, Murali, Johnson-Obaseki, Stephanie, Eapen, Libni, Odell, Michael, Chandarana, Shamir, Banerjee, Robyn, Dort, Joseph, Matthews, T. Wayne, Hart, Robert, Kerr, Paul, Dowthwaite, Samuel, Gupta, Michael, Zhang, Han, Wright, Jim, Parker, Christina, Wehrli, Bret, Kwan, Keith, Theurer, Julie, Palma, David A.
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2020
נושאים:
Study Protocol
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023689/
https://ncbi.nlm.nih.gov/pubmed/32059705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6607-z
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