Vitamin B(12b) Enhances the Cytotoxicity of Diethyldithiocarbamate in a Synergistic Manner, Inducing the Paraptosis-Like Death of Human Larynx Carcinoma Cells

We have shown that hydroxycobalamin (vitamin B(12b)) increases the toxicity of diethyldithiocarbamate (DDC) to tumor cells by catalyzing the formation of disulfiram (DSF) oxi-derivatives. The purpose of this study was to elucidate the mechanism of tumor cell death induced by the combination DDC + B(...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Solovieva, Marina, Shatalin, Yuri, Fadeev, Roman, Krestinina, Olga, Baburina, Yulia, Kruglov, Alexey, Kharechkina, Ekaterina, Kobyakova, Margarita, Rogachevsky, Vadim, Shishkova, Elena, Akatov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023477/
https://ncbi.nlm.nih.gov/pubmed/31906414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010069
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados