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Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s disease (PD) following nasal administration. In this study, we use...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Zhang, Rui, Wu, Jie, Liu, Siyu, Deng, LiangJun, Hu, Junhua, Chen, Xi, Tan, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023290/
https://ncbi.nlm.nih.gov/pubmed/31906459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010035
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