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Directly Compressed Tablets of Free Acid Ibuprofen with Nanocellulose Featuring Enhanced Dissolution: A Side-by-Side Comparison with Commercial Oral Dosage Forms

We have previously reported that heated powder mixtures of ibuprofen (IBU) and high surface area nanocellulose exhibit an enhanced dissolution and solubility of the drug due to IBU amorphization. The goal of the present work was to further elaborate the concept and conduct side-by-side in vitro drug...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Mantas, Athanasios, Petit, Marie-Amélie, Mihranyan, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023118/
https://ncbi.nlm.nih.gov/pubmed/31963396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010071
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