Identification of the NADP(+) Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from Giardia lamblia

Giardia lambia is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that G. lamblia exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate pathway (PPP). Our group work demonstrated tha...

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Udgivet i:Biomolecules
Main Authors: Morales-Luna, Laura, González-Valdez, Abigail, Sixto-López, Yudibeth, Correa-Basurto, José, Hernández-Ochoa, Beatriz, Cárdenas-Rodríguez, Noemí, Castillo-Rodríguez, Rosa Angélica, Ortega-Cuellar, Daniel, Arreguin-Espinosa, Roberto, Pérez de la Cruz, Verónica, Serrano-Posada, Hugo, Centeno-Leija, Sara, Rocha-Ramírez, Luz María, Sierra-Palacios, Edgar, Montiel-González, Alba Mónica, Rufino-González, Yadira, Marcial-Quino, Jaime, Gómez-Manzo, Saúl
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022596/
https://ncbi.nlm.nih.gov/pubmed/31892224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010046
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