Effective Targeting of Colon Cancer Cells with Piperine Natural Anticancer Prodrug Using Functionalized Clusters of Hydroxyapatite Nanoparticles

Targeted drug delivery offers great opportunities for treating cancer. Here, we developed a novel anticancer targeted delivery system for piperine (Pip), an alkaloid prodrug derived from black pepper that exhibits anticancer effects. The tailored delivery system comprises aggregated hydroxyapatite n...

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Vydáno v:Pharmaceutics
Hlavní autoři: AbouAitah, Khaled, Stefanek, Agata, Higazy, Iman M., Janczewska, Magdalena, Swiderska-Sroda, Anna, Chodara, Agnieszka, Wojnarowicz, Jacek, Szałaj, Urszula, Shahein, Samar A., Aboul-Enein, Ahmed M., Abou-Elella, Faten, Gierlotka, Stanislaw, Ciach, Tomasz, Lojkowski, Witold
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022489/
https://ncbi.nlm.nih.gov/pubmed/31963155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010070
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