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Kaposi’s Sarcoma-Associated Herpesvirus Viral Interleukin-6 Signaling Upregulates Integrin β3 Levels and Is Dependent on STAT3

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of two B-cell lymphoproliferative diseases and Kaposi’s sarcoma, an endothelial-cell-driven cancer. KSHV viral interleukin-6 (vIL-6) is a viral homolog of human IL-6 (hIL-6) that is expressed in KSHV-associated malignancies. Previ...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Rivera-Soto, Ricardo, Dissinger, Nathan J., Damania, Blossom
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022358/
https://ncbi.nlm.nih.gov/pubmed/31801855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01384-19
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