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Optimization of Rifapentine-Loaded Lipid Nanoparticles Using a Quality-by-Design Strategy

This work aims to optimize and assess the potential use of lipid nanoparticles, namely nanostructured lipid carriers (NLCs), as drug delivery systems of rifapentine (RPT) for the treatment of tuberculosis (TB). A Box–Behnken design was used to increase drug encapsulation efficiency (EE) and loading...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Magalhães, Joana, L. Chaves, Luise, C. Vieira, Alexandre, G. Santos, Susana, Pinheiro, Marina, Reis, Salette
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022298/
https://ncbi.nlm.nih.gov/pubmed/31963468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12010075
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