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Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study

INTRODUCTION: The B cell survival factor B lymphocyte stimulator (BLyS) is elevated in patients with systemic lupus erythematosus (SLE) and associated with disease activity. Belimumab, a monoclonal antibody specific for soluble BLyS, is approved for the treatment of adults with active, autoantibody-...

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Detalhes bibliográficos
Publicado no:Rheumatol Ther
Main Authors: Zhang, Jing, Wan, Weiguo, Miao, Liyan, Wu, Jian, Dong, Jun, Shen, Yinghua, Xiong, Cui, Li, Chao, Xue, Yu, Cao, Guoying, Ma, Peiming
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021845/
https://ncbi.nlm.nih.gov/pubmed/31953740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40744-020-00193-9
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