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Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

Compulsive eating characterizes many binge-related eating disorders, yet its neurobiological basis is poorly understood. The insular cortex subserves visceral-emotional functions, including taste processing, and is implicated in drug craving and relapse. Here, via optoinhibition, we implicate projec...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Spierling, Samantha, de Guglielmo, Giordano, Kirson, Dean, Kreisler, Alison, Roberto, Marisa, George, Olivier, Zorrilla, Eric P.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021713/
https://ncbi.nlm.nih.gov/pubmed/31593982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0538-x
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