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Analysis of Yeast Killer Toxin K1 Precursor Processing via Site-Directed Mutagenesis: Implications for Toxicity and Immunity

K1 represents a heterodimeric A/B toxin secreted by virus-infected Saccharomyces cerevisiae strains. In a two-staged receptor-mediated process, the ionophoric activity of K1 leads to an uncontrolled influx of protons, culminating in the breakdown of the cellular transmembrane potential of sensitive...

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Bibliografske podrobnosti
izdano v:mSphere
Main Authors: Gier, Stefanie, Schmitt, Manfred J., Breinig, Frank
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021474/
https://ncbi.nlm.nih.gov/pubmed/32051241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00979-19
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