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Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease

Insulin-signalling is an important pathway in multiple cellular functions and organismal ageing across the taxa. A strong association of insulin-signalling with Parkinson’s disease (PD) has been proposed but the exact nature of molecular events and genetic associations are yet to be understood. We e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Haque, Rizwanul, Shamsuzzama, Kumar, Lalit, Sharma, Tanuj, Fatima, Soobiya, Jadiya, Pooja, Siddiqi, Mohammad I., Nazir, Aamir
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021237/
https://ncbi.nlm.nih.gov/pubmed/32110282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27366
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