In vitro selection of aztreonam/avibactam resistance in dual-carbapenemase-producing Klebsiella pneumoniae

OBJECTIVES: To examine the in vitro selection of aztreonam/avibactam resistance among MBL-producing Klebsiella pneumoniae and to understand the mechanism of increased resistance. METHODS: The MICs of aztreonam were determined with and without avibactam (4 mg/L) using a broth microdilution method. Si...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Niu, Siqiang, Wei, Jie, Zou, Chunhong, Chavda, Kalyan D, Lv, Jingnan, Zhang, Haifang, Du, Hong, Tang, Yi-Wei, Pitout, Johann D D, Bonomo, Robert A, Kreiswirth, Barry N, Chen, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021086/
https://ncbi.nlm.nih.gov/pubmed/31722380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz468
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