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Single molecule sensing of amyloid-β aggregation by confined glass nanopores

We have developed a glass nanopore based single molecule tool to investigate the dynamic oligomerization and aggregation process of Aβ1–42 peptides. The intrinsic differences in the molecular size and surface charge of amyloid aggregated states could be distinguished through single molecule induced...

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Vydáno v:Chem Sci
Hlavní autoři: Yu, Ru-Jia, Lu, Si-Min, Xu, Su-Wen, Li, Yuan-Jie, Xu, Qun, Ying, Yi-Lun, Long, Yi-Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020925/
https://ncbi.nlm.nih.gov/pubmed/32153747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03260f
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