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Single molecule sensing of amyloid-β aggregation by confined glass nanopores

We have developed a glass nanopore based single molecule tool to investigate the dynamic oligomerization and aggregation process of Aβ1–42 peptides. The intrinsic differences in the molecular size and surface charge of amyloid aggregated states could be distinguished through single molecule induced...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Yu, Ru-Jia, Lu, Si-Min, Xu, Su-Wen, Li, Yuan-Jie, Xu, Qun, Ying, Yi-Lun, Long, Yi-Tao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020925/
https://ncbi.nlm.nih.gov/pubmed/32153747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03260f
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