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Analysis of Longitudinal‐Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models

Longitudinal‐ordered categorical data, common in clinical trials, can be effectively analyzed with nonlinear mixed effect models. In this article, we systematically evaluated the performance of three different models in longitudinal muscle spasm adverse event (AE) data obtained from a clinical trial...

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Foilsithe in:CPT Pharmacometrics Syst Pharmacol
Main Authors: Lu, Tong, Yang, Yujie, Jin, Jin Y., Kågedal, Matts
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020275/
https://ncbi.nlm.nih.gov/pubmed/31877239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12487
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